Hormone Therapy Update!


Breast Cancer is a major health issue. It is the most common cancer-related cause of death in women.   World-wide about 1,670,000 women have breast cancer. And in North America, a woman dies of breast cancer every 12 minutes!

There is only a very slight chance is of getting breast cancer from a virus.   The primary factor is toxic chemicals that we come in contact with everyday. Chlorine and its thousands of deadly byproducts everywhere. Water is the primary source and chlorine is a primary cause.

Your endocrine system produces a host of hormones and is a delicate orchestrated machine, designed to help you grow, develop and reproduce. 

In women, estrogen is the primary female hormone.  When unbalanced by adequate levels of progesterone, estrogen can be very deadly, turning on the body and triggering mutenagenic cell growth leading to cancer.

   Progesterone      Breast Cancer    

Urgent call on HRT

It's official. Synthetic hormone replacement therapy (HRT) is no longer considered 'safe' when used long term, and increases the risk of cancer and heart disease. Links of HRT to breast cancer, stroke and other diseases has caused widespread panic.  US research should be taken seriously.

It is recommended, women who have been using oral estrogen plus progestins (not to be confused with bio-identical progesterone) for less than five years should not be concerned, but should have their therapy reviewed each year.

The US study on the risks of combined estrogen-progestin was called off because of fears for its participants. The trial was cut short after five years because it was found one in 100 women taking the HRT combination suffered health consequences, including breast cancer and heart disease. The US findings could have legal implications for the manufacturers of HRT drugs.

Prescriptions for Premarin  and for Provera are used it to alleviate symptoms of menopause. A much smaller percentage of women take it to prevent chronic diseases such as osteoporosis. 


Progestin is confused with Progesterone

Women should heed warnings that hormone replacement therapy can cause serious illness, and export medical committee found last night (July 12, 2002).   The urgently-convened panel ruled that combined HRT should not be used by women in the long term. It backed US findings that combined estrogen and progestin increases the risk of heart disease, breast cancer and stroke.  

HRT - Why were we told to take HRT  ?

The  recent  findings are that HRT can increase the risk of heart disease and breast cancer. HRT has been widely promoted as a safe remedy now we are finding it is not safe at all.

Women must seek additional advice,  trusting in your doctor, could be very damaging.   Pharmaceutical companies are the main source of information for many doctors. Pharmaceutical companies have an interest in selling their products and they do this by heavily promoting drugs, including HRT to doctors. The question is whether doctors are getting balanced information or just promotional material from the pharmaceutical companies.

Some Doctors receive payments from pharmaceutical companies, for filling out questionnaires and reviewing patient therapy. There maybe bias in their reporting. Muddying the waters are caused by mixed expert medical opinions.   When doctors, have a financial relationship with pharmaceutical companies their expert opinion can be influenced and should be questioned.  

1997 British Medical Journal review of 22 studies concluded that there was no evidence that post-menopausal HRT prevents heart and blood vessel problems. Until recently women weren’t given this information, but were told that HRT could protect them from heart disease.

Consumers are right to ask “Why weren’t these products tested more thoroughly before they were prescribed so broadly and why weren’t we told of the possible risks earlier ? 

Don't Confuse Progestogens with Progesterone

Some doctors, on the other hand, mistakenly believe they are already prescribing progesterone to women when, in fact, they are issuing a prescription for progestins/Progestogens. These doctors have been fed a lot of mistruths, compounded by misrepresentation on the part of the drug companies who are leading doctors to believe their particular brand of Progestogens is a 'natural' progesterone or derived from 'natural' compounds. This is stretching the truth somewhat because they have failed to explain to the doctors how these natural ingredients have been molecularly tampered with and are no longer 'natural' or bio-identical to the body. Little wonder confusion reigns out there. And little wonder doctors are even more confused when a woman arrives in the surgery demanding a script for natural progesterone.

Many doctors don't understand the difference between progesterone and a synthetic Progestogens, so therein lies a problem to start with. The second problem lies in the fact doctors do not take kindly to being told they might be wrong. They don't appreciate their patients turning up with more information on a drug like progesterone which they have failed to research. This deflates their ego and/or threatens them. Thirdly, a doctor is trained a specific way and has developed a certain mind set.

Estrogen and hormones of the reproductive system

With age, the human body changes and hormone production declines. A lot of attention has been given to HGH (Human Growth Hormone), Estrogen, Progesterone, Melatonin and DHEA  for women and HGH, Testosterone, Melatonin and DHEA for men. The internet is packed with information on HRT mostly focused on Anti-aging and rejuvenating a persons declining Endocrine System. These same products and related prohormones that have been used in the body building industry for many years.  Improper use and abuse of hormones can cause the body to shut down its normal production and will lead to increased production of harmful and unwanted hormones. 

Supplemental dosage levels for HRT are much lower than that used for body building and hormones that are bio-identical appear to be safe and free of side affects when used in moderation.

The search for health rejuvenation and to turn back the hands of time is difficult for many. The hopeful ideal is to lose wait, increase mussel mass, and regain the vitality of youth. So many infomercials and ads offering very questionable products. It is better to spend a lot of money and get no results than any amount and have bad results. Caution must be taken when purchasing products that offer hormone stimulators and precursors.  If the product makes claims to be a hormone replacement, then it should be a real hormone.

"Fact-Progestogens are similar to progesterone they are natural and produced by the Ovary" Similar does not mean the same. Progestogens cause birth defects Progesterone does not.  


Endoprin is a Progesterone Supplement      

Endoprin contains Progesterone, with an blend of supporting natural hormones. The formula is primarily progesterone stacked to improve the effectiveness while allowing for lower dosages.  

Most women over the age of 30 need supplemental hormone therapy. The danger of breast cancer comes from exposure to toxic chemicals which trigger detrimental affects to the cell by estrogen. Progesterone has a balancing affect and helps to overcome estrogens out of control nature.

How is Endoprin usually taken?  

  • Skin infusion as a topical oil 
  • Sublingually, under the

Is Endoprin addictive?

Do women experience any side effects coming off Endoprin ? Based on observation, "no". Women who stopped using natural progesterone cream were not bothered by drug-related 'withdrawal' symptoms. Rather, they reported a resurgence of their estrogen dominance symptoms indicating their body genuinely required natural progesterone supplementation to support their hormone balance.

Women who withdraw from estrogen use do experience very distressing side effects as a result of estrogen levels dropping and the brain being conditioned to  "an estrogen conditioned threshold". The body appears to be conditioned to high levels of estrogen, and variance appears to trigger a reemergence of symptoms with a vengeance. Depression and anxiety surface, often peaking at around 3 months after discontinuing estrogen.   Endoprin does not contain estrogen only progesterone to support the bodies natural estrogen.

Long term estrogen users need to 'wean' off estrogen slowly in order to allow the biofeedback mechanism in the body to adjust, and allow for adequate time for natural progesterone to saturate the body and to buffer this huge ratio difference. Women who go off estrogen therapy 'cold turkey' find it a very uncomfortable experience, and may want to return to estrogen use despite all their previous side effects purely because they are unable to cope with the inevitable withdrawal and associated menopausal symptoms which appear to be far worse than those faced by women going through a difficult menopause 'naturally'.

Interestingly, many women who stop taking synthetic Progestogens tablets after experiencing negative side effects usually feel instant relief, especially if they replace Progestogens with bio-identical progesterone. We have not seen evidence of actual withdrawal symptoms coming off synthetic Progestogens other than the thickening of the uterine lining, particularly if estrogen is continued.

Continued use of estrogen will dominate the hormone environment allowing the potential problem of uterine buildup to occur whilst that woman is being weaned off estrogen. This is when initial high levels of natural progesterone (10%) may be called for until there is a balanced ratio between estrogen and progesterone. A reduction program of progesterone is required in accordance to the reduction of estrogen levels in the body. And it's only when a woman has totally weaned off estrogen and is a symptomatic for 4 months will she then be able to establish her true physiological dose of progesterone (around 20-32mg). There have been cases where, after 4 months, symptoms have not abated and a very small dose of natural estrogen was required.

Use hormone blood profiles to ascertain levels. It's important to make sure that your progesterone is actually opposing uterine buildup. So work closely with your doctor, and have the required tests that keep a check on this.

Important: As you wean off estrogen you must take a break from estrogen at the same time you take a break from progesterone, otherwise estrogen dominance will reside which has the potential to cause uterine problems.

Possible risks and side effects of The Pill and incorrect HRT:

  • Allergic reactions
  • Birth defects
  • Breakthrough bleeding
  • Decreased immune system function
  • Disturbances in liver function
  • Eye disorders (double vision, swelling of optic nerve, contact lens intolerance, corneal inflammation)
  • Facial and body hair growth
  • Fluid retention and bloating
  • Fungal infections 
  • Infertility increased with The Pill
  • Irritable bowel syndrome
  • Hair loss
  • Hay fever, asthma and skin rashes
  • Loss of Libido
  • Lumpy and tender breasts (fibrocystic breasts)
  • Migraines and headaches
  • Nausea
  • Nutritional deficiencies especially zinc, B6 and magnesium
  • Psychological and emotional disorders, depression, mood changes
  • Secretions from breasts
  • Skin discoloration
  • Higher rates of suicide
  • Weight gain
  • Candida infection
  • Urinary tract infection
  • Venereal warts
  • Vaginal discharges (increased incidence of vaginal thrush)
  • Fatigue
More serious effects of The Pill and incorrect HRT:
  • Disturbance of blood-sugar metabolism (contributing to diabetes and hypoglycemia)
  • Increased incidence of thrombosis (stroke)
  • Increased incidence of hardening of the arteries and high blood pressure
  • Increased risk of blood clots
  • Increased risk of gall bladder and liver disease
  • Increased incidence of cancer of the breast, endometrium, cervix, ovaries, liver, lung and skin
  • Increased risk of heart attacks
  • Increased incidence of MS

Possible risks and side effects of natural progesterone:

  • Because progesterone topical oil contains the hormone identical to that produced by the human ovary, side effects are usually minimal. If experienced these may include breast tenderness and swelling, fluid retention or slight vaginal bleeding. Dizziness, nausea, fatigue, headaches and light headedness have been reported occasionally and usually disappear with adjustment of dose.

  • Progesterone is the hormone essential for promotion and maintenance of pregnancy. Ovarian output of progesterone in the non-pregnant state is 25-30mg daily during the luteal phase. The placental output during the third trimester of pregnancy is 340-400mg per day. Where as progestagens are contraindicated in pregnancy progesterone exhibits no adverse effects on the fetus.

Types of HRT regimes that might be offered by your doctor:
  • estrogen only - usually only recommended for women who have had a hysterectomy (can be natural or synthetic)

  • estrogen + Progestogens - usually recommended for women with intact uterus to protect the endometrium (lining of the uterus)

  • sequential or cyclic treatments - estrogen taken 7-14 days followed by Progestogens 10-14 days, resulting in a period after the Progestogens dose is taken. Usually recommended for premenopausal women to control menopausal symptoms and to regulate bleeding whilst protecting the endometrium.

  • Continuous combined - estrogen and Progestogens continually to prevent the thickening of the lining of the uterus without incurring a bleed. Usually for women 2 years post-menopause who do not wish to have a period in their therapy.

  • Progestogens - oral pill or injection, combination varies for specific purposes and treatment such as contraception, perhaps endometriosis, PCOS.

Alternative therapies

Drug companies (via your doctor's surgery) scare women into believing that diseases such as osteoporosis and heart disease are inevitable consequences of menopause. They advocate that while alternative therapies may relieve some symptoms of menopause for some women, they are not HRT and do not replace the vital hormones required by the body to function well and prevent diseases. They claim that many of these over-the-counter medications and products derived from Soya beans, wild yam, evening primrose, red clover, etc., are not researched or tested to the same standards as conventional drugs and the effects of these remedies, long term, have not been established.

Not true, we've seen many successes where women have adopted alternative therapies without the need for hormone replacement. These over-the-counter remedies (knowledge of which dates back centuries) have provided women with effective alternatives that enhance hormonal health and balance, rejuvenated their energy and stamina, supported their metabolism, aided weight loss, and counter-balanced depression and anxiety, and insomnia. This has been as simple as incorporating a balanced phytoestrogenic formulation, increasing their essential oils, supporting liver and adrenal functioning through vitamin, mineral and liver formulation, acknowledging their body type, and eating foods that are compatible to their their hormonal and metabolic characteristics. We've also noted in some women a drop in cholesterol, blood pressure and fluid retention. So while drug companies may claim there's no proof, our website certainly has empirical evidence to the contrary.

Let's state up front that not every women approaching or in menopause needs hormone replacement therapy, be it via any of the natural hormones or conventional synthetic HRT. Their diet, exercise and lifestyle can carry them through, disease-free, to old age. These fortunate people are free of disease, have good bones, and maintain hormonal harmony from the foods they eat which contain plant hormones known as phyto-sterols that have a balancing effect upon their cell receptors. In a body functioning optimally, hormones are manufactured by the ovaries, adrenal glands, fat tissue, thyroid and pineal glands. Only when the sex hormones are out of balance in the body is there a need for hormone replacement therapy. And at this point you would thoroughly consider all your options.

We see so many women entering menopause or post-menopausal who were a symptomatic but were placed on HRT as a preventative measure, only to be faced with a host of new health issues ranging from weight gain, high cholesterol, headaches, fluid retention, irritability, etc., none of which were pre-existing prior to HRT.

Women considered low risk and possibly do not require hrt are women that:
  • Have good bones - medium to heavy bone structure
  • Do not have osteoporosis (or family history)
  • Do not have cardiovascular disease (heart, stroke, embolisms) (or family history)
  • Do not smoke
  • Do not suffer depression
  • Do not use drugs that might increase bone loss (steroids, thyroid medication, diuretics, antacids)
  • Have an intact uterus and ovaries (no history of tubal ligation)
  • Correct weight to height ratio
  • Good cholesterol and blood pressure reading, normal functioning thyroid
  • Exercise regularly
  • Have a healthy diet rich in fresh fruit and vegetables, low-saturated fat diet,
  • Enter menopause between 45-45 years of age
  • Have no estrogen dominance symptoms or history of PMS
  • Have a happy disposition and good relationship

Confused which form of hormone replacement therapy you should use?

You need to conduct your own research - don't accept everything you read or hear. The natural  forms of hormone replacement therapy include: progesterone, estrogen, testosterone, DHEA pregnenolone and the corticosteroids (the 'super' anti-aging hormones). These bio-identical hormones are less imposing on the body and kinder on your liver.

Our fundamental focus for women is essentially natural progesterone.    We believe natural progesterone is quite an incredible and remarkable hormone, discovered by millions of women worldwide.  


Disclaimer: We are not medical professionals and this information came from various sources in our own research. It is for information purposes only and is not a prescription for your particular needs. Consult with your health care professional if in doubt or if you have questions. We do not diagnose or try to overrule the advice of your health care professional.